My husband took vectibix . His side effects were the rash and acne on his face. He said it felt like his face was burning. Looked like he had a bad sunburn.He also had some mouth sores that made it hard to eat and he pretty much stopped eating. He lost a bunch of weight, so pack on the pounds if you can. After a couple bags of fluid, and dr stopped the infusion to give him a break. Unfortunately it did not cure his cancer .colon (cancer metastasized to his lungs.) Prayers and best of luck!