← Return to Anyone else with ET have mutation in MPL gene?

Discussion

Anyone else with ET have mutation in MPL gene?

Blood Cancers & Disorders | Last Active: Jan 31 1:06pm | Replies (6)
Comment receiving replies
@jacquelineh

I’m female, 63, with MPL mutation. My platelets were 1073 in February 2022, now 453. Pretty similar to you.
I’ve been on low dose aspirin and Hydroxy 500/1000 alternate days since Feb.
Worst side effects have been headaches and brain fog/chemo brain … very difficult to live with.
My understanding has been that MPL is the most rare but also the least concerning of the three mutations and that JAK2 is the really problematic one.
I’m in NZ and have been badly served by our public health system with our shortage of doctors so I’m intending to get a referral to a specialist now.

Jump to this post

Replies to "I’m female, 63, with MPL mutation. My platelets were 1073 in February 2022, now 453. Pretty..."
kapow | @kapow | Jan 31 12:35pm

Thank you for this. I didn't realize that MPL was the least concerning, but that is reassuring.
And the brain fog/chemo brain you talk about....I wonder if that is maybe what I have too? I will be talking and in the middle of a sentence I can't find a word so have to reorganize my thoughts and work around the misplaced word. Or someone helps me with the missing word. Or I just pause for longger mis-sentence until the word magically appears. This happens frequently, and most of my frends tell me that it happens to them too, but I swear it seems much more frequent to me than to others. Is this sort of thing reflective of Chemo brain?

VIEW AND REPLY