Hello, kapow! Congratulations on getting your platelets down!

I too am a 69 year-old female with the MPL mutation. There aren't many of us with this version of ET, so unfortunately we have even less research on symptoms, efficacy of treatment, etc. to help us.

They say misery loves company, so I'll share that I have a headache almost all the time. Using a lidocaine spray on the back of my neck helps some. I've been assured that using lidocaine (which works through the skin) doesn't interfere with the low-dose aspirin I take every morning.

Debhammel is right: it's important to tell your doctor about your headaches since this is a new problem.

You need guidance on what you can safely do to relieve your headaches.

Glad you've found this forum.