I was in NJH in Denver over 5000 ft and the saturation goes down by 3-4 %. But I kept it around 92% so there was no need for the oxygen. We made a short trip to see the ski resort around 9000 ft and I was short of breath and walking was a challenge. So I would say consider all the elements such as your saturation level, shortness of breath but definitely your saturation level will go down.