Prior to my lumpectomy, I was using Estradiol every couple of days because i have a history of frequent UTIs. The Estradiol was applied externally every couple of nights before bed. My oncologist directed me to stop using it, obviously because it contained estrogen. That was May 2022 when I started on anastrozole and I was good for awhile but late last year, had a couple of utis right in a row. In response to my concern about not being able to use it, my PA recommended coconut oil. I now use it every night and although one uti did sneak in, I’ve been good otherwise. You can google and see that coconut oil does offer protection..