If 4 clicks is tolerable you are in good shape! Four is therapeutic, I was told, but of course the more the better. In the beginning I could not even tolerate 4 but I eventually got to 7. I did do the full 8 toward the end! I also varied between 6. 7 and 8 clicks depending on what I had to do. Some days , no side effects, other days there were- who knows why.

I have low blood pressure so for awhile I checked it afterward because low bp from the shot can cause some of the symptoms. I drank water and sometimes ate something salty for the hour before. I have occasional afib but Tymlos did not trigger it at all.

When I did it at night, I would wake with a horrific headache. But that was at the higher dose that I first tried. I did find that symptoms were better if I got up and out, which is kind of counter-intuitive. At first I would lie in bed and feel woozy. Then I tried getting up and going about my day and for some reason felt better. We are all different! I guess the point is we can play around with things to make it work 🙂 Good luck!

@bella0923
Like you, I could not tolerate the full dose at first. Headaches (bad ones), fatigue, increased heart rate. My doctor told me to dial it down to 40mcg, and I was fine on that dose. I clicked up to 50 after 1 month and then 60 about 3 weeks later. I sometimes took 1 Advil 2 hours before injection, and that helped avoid headaches the first few nights after upping my dose. I could stop the nightly Advil after a week. Last night I tried 70 mcg with no Advil, and I felt the same as I did on 60. My body just had to get used to the medication. As @windyshores said, we do expect some side effects, but the key is finding a tolerable level. Every 3-4 weeks has been a good timetable for me to bump up my dose. My body just takes that long to get used to things. In 10 days, I have my first blood test since starting on Tymlos. I’m hopeful that increasing the dose this way will prove effective.