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Replies to "Reclast is the recommended bisphosphonate following Prolia. It will remain in the bones and blunt the..."
I am terrified at the thought of putting in a year's dose of drug into my body through infusion. Also, for Reclast to be effective as a relay drug, the correct timing would have to be determined with the help of bone turnover markers which my doctor is not willing or unable to order. For these reasons, i decided on Alendronate instead. If it's true that Reclast stays in the body for only 2 years, that's a huge plus. I have read that Alendronate can remain for years, even decades after
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“ Combined treatment with teriparatide 40 μg and denosumab increases spine and hip BMD more than standard combination therapy. This large and rapid increase in bone mass suggest that this high dose regimen might provide a method of restoring skeletal integrity in patients with osteoporosis."
Yes, Reclast is often recommended as the relay drug following Prolia. And i believe Dr McCormick is of the opinion that once you have taken 3 or more shots of Prolia, Reclast would be required as Alendronate would not be potent enough to mitigate the rebound effect