@flor we took your questions about medications for latent TB and their side effects to a pharmacist here at Mayo Clinic. She writes: Common medications used for latent TB include isoniazid and rifampin. Sometimes a person will use one or the other, and sometimes they are used together. Usual treatment lasts for 6 to 9 months for isoniazid alone, lasts for 4 months if on rifampin alone, or lasts for 3 months if taking them together.
Isoniazid may increase the blood pressure, cause liver problems, skin rash, nausea, vomiting, diarrhea, swelling of breast tissue in males, vision problems, and vitamin B6 deficiency which may lead to peripheral neuropathy. It is sometimes recommended that a person taking isoniazid long term should also take a B6 supplement due to this side effect.
Rifampin must be taken on an empty stomach and can also affect the liver, cause stomach upset and rash. Less common side effects include swelling, flushing, itchy skin, muscle pain and weakness, fatigue, vision problems, and kidney problems.
When on either of these medications it is common to have routine bloodwork to monitor the kidneys and liver. It is also important to avoid alcohol and discuss all medications with your doctor or pharmacist as there may be a number of drug interactions.
Do you know if your family members are familiar with any of these drugs or have tried any yet?