Hi @leper. Welcome to Connect, an online community where you can find support from others who have been there. We are glad you are here. I did some research on Efudex and it sounds like it can be a long-term solution if your doctor recommends continued use and if it seems to be working. Do you find that it helps?

In terms of side effects, most are the typical ones you'd expect: skin irritation, burning, redness, dryness, pain, swelling, tenderness, or changes in skin color may occur at the site of application. Other side effects include eye irritation, trouble sleeping, irritability, temporary hair loss, or abnormal taste in the mouth. Rare but serious side effects include stomach/abdominal pain, bloody diarrhea, vomiting, signs of infection, easy bruising/bleeding and mouth sores, so if you notice any of those, definitely talk to your doctor immediately.

I'm also tagging @mlemieux who has dealt with skin issues and may be able to provide some tips. Hope this helps!