Hi, @floridawilbur. Sorry to hear that you've been left in the lurch by a doctor's switch in hypertension medication away from Carvedilol to Chlorthalidone. I've been on Carvedilol for several years, but almost from the beginning at the same dosage as now (25mg twice a day). So I don't have personal experience with the side effects you mentioned -- and which several dozen Connect members have posted sad experiences with abrupt reduction or termination in the dosage. As a hypertension victim, I've been on over a dozen different medications over the years, Chlorthalidone included, but that diuretic was replaced with a unique potassium-sparing diuretic (Amiloride) when my inherited kidney problem was discovered (they dump potassium and don't reclaim it). I had the good fortune of being referred to a nephrologist by my medical team, and that led to detailed tests of my blood and hormones by an endocrinologist, working with my nephrologist. They figured me out, and their therapy for me was way different from what I was offered by a series of cardiologists. I can't imagine life without a good nephrologist to turn to when my BP wanders off its safe level or a primary care physician who recognizes the role of hormones in hypertension. Perhaps those specialties could be helpful to you as well. Martin