I know my response is months late, but I had exactly the same experience. 3 days after starting Letrozole, my heretofore insignificant neuropathy, which was only in my toes and fading, significantly worsened to involve the bottoms of my entire foot, my hands, and my balance. My doc's nurse told me it is "unlikely" that it was the Letrozole after only 3 days. I wrote back and said, okay, assuming it's not the Letrozole, I've still got the problem and what could be causing it? I went through this with the steroid infusion, told for weeks that my 3 days of horrible symptoms, including 72 hours of night sweats, were depression. That is stupid on its face. I also was not warned about the ethanol in the docetaxel solution, and had to figure out on my own that I was drunk after being sober for 13 years. Fortunately, my husband always drove, but involuntary intoxication is a defense to drunk driving or, God forbid, killing someone with your car. Your oncologist or hospital will have no such defense. Oncologists are shocked -- shocked! -- by the breast cancer patient experience. Frankly, I'm disgusted that they're shocked. Did they listen to their patients at all during the 20-30 years they were practicing oncologists before breast cancer happened to them? The oncologists are also shocked when they are not listened to, either. Some of those oncologists try to monetize their experience by starting Youtube channels and writing books. They think, since they're oncologists, they're uniquely positioned to explain the things that happen to all of us.