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What are most common side effects when starting HU (Hydroxyurea)?

Blood Cancers & Disorders | Last Active: Mar 3 8:38am | Replies (53)
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@beebo

I’m on HU since October 2021 for PV and currently taking 500 mg 4x week. Have never had any side effects except once when I dropped a capsule in a glass of water and it got partially dissolved. Had a major case of the itches after I took that dose. I really think it has reduced the number of phlebotomy treatments that I started out with following my diagnosis.

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Replies to "I’m on HU since October 2021 for PV and currently taking 500 mg 4x week. Have..."
jerrlin | @jerrlin | Jan 23 7:16am

That is really interesting. I am on three 500 mg capsules a week and until my counts stabilize, we will keep adjusting it. The disappointing thing is, I still haven’t found anything for when I have severe itching attacks. I take antihistamines and ibuprofen that helps a little, but they still last about a half hour then I’m done for the day. It’s crazy because I don’t even have to be by water. Have you found anything that helps the itching?

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