I also had vasculitis. My rheumatologist knew that I needed to be on steroids but also wanted to try cytoxan (which is also used for myeloma). It worked and brought down my myeloma numbers. The rheumatologist felt that I should get treatment for the myeloma and it would also help with the Vasculitis. Is there advantages to getting treatment earlier? I am not sure, but I have never had any bone damage or renal disease and it has been going on six years now since the diagnosis. It might of never progressed without treatment but who knows.