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Generalized motility disorder

Posted by truthfinder @truthfinder, Sep 15, 2025

I have reflux,gastric emptying delay and constipation and was recently diagnosed with generalized motility disorder.Omeprazole is helping my reflux and Motegrity was helping my constipation for about 5 weeks until it didn’t,now my constipation is worse and I’ve become laxative dependent and developed constant rectal pressure,is anybody out there in a similar situation with any advice?

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cara354 | @cara354 | Sep 29, 2025
In reply to @truthfinder "I recently got diagnosed with generalized motility disorder.My reflux is controlled by Omeprazole.I also have moderate..." + (show)
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I recently got diagnosed with generalized motility disorder.My reflux is controlled by Omeprazole.I also have moderate gastroparesis and constipation and rectocele.For 5 weeks Motegrity was working well for the constipation,until I developed rectal pressure almost daily and constipation is worse.The GI doctor ordered anorectal manometry and MR defecography,pelvic floor therapy and to take Miralax everyday which seems to work well so far.It sucks having this problem and having my birthday tomorrow.Has anybody had these tests and taking Miralax long term? I am a nurse and going back to work soon,it is so hard to help others if you cannot help yourself.I am hoping for some improvment and a better quality of life.It is so hard that I cannot eat any of the food that I culturally grew up with due to this gastroparesis.

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@truthfinder uggg I have gastroparesis ibs,acid reflux, most of my adult life in early 20s and now im 71. I actually found a better probiotic and switched to that. Stonehedge sells it. I also occasionally take lincess, which helps. But dont need it too often. The Amazon gummie fiber chews help. 2 a day. But I get my days. Where im eating papaya enzyme like candy, every day is an adventure. I was doing well on 1 scoop.of collagen powder, grass fed. I only drink decafe coffee and decafe green tea. Several bottles of spring water a day. Also eliminated as much food with dyes as possible. Even my otc meds no dyes except the 2 gummies. Its all a process and sadly it changes daily. I do double up on my pro biotic if im having a bad day.

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truthfinder | @truthfinder | Dec 9, 2025

I was recently diagnosed with generalized motility disorder(reflux,gastroparesis,constipation) and now fibroscan ultrasound showed F2 liver fibrosis,saw my GI doctor and he said,diet and exercise,lose more weight and that the liver and motility problem are separate with each other,I am worrried,I’ve right sided abd pain,bloating,reflux,constipation,muscle pain in knees and legs on and off,anybody in a similar situation? Advice?

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