Research Opportunity: Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection

The purpose of this study is to assess the acceptability of vaginal fluid collection for a DNA-based endometrial cancer detection test.

Why This Research Is Important

It is important to know if women among underrepresented groups are comfortable with tests using DNA from vaginal fluid. Specifically, Black women are underrepresented in gynecologic cancers clinical trials and treatment standards are often determined without appropriate representation of this most affected group.

Who Should Consider Participating

People who identify as a Black woman, are 45 years of age or older with a uterus that has not been removed.

What Happens If You Participate In The Study

You will be in the study from the signing of the informed consent form until the completion of the approximately 30-minute virtual study interview.

• Virtual Screening visit:

A virtual screening visit will occur to obtain consent and collect demographic information including age, education level, employment status, household income and insurance status.

• Virtual Visit 1:

Each person who agrees to be in the study will have a 30-minute virtual interview. The questions will be mostly open-ended with some directed questions to ensure information needed for the research study is collected. Interviews will be recorded and transcribed exactly as things
were said.

Potential Risks

Study Interview:

• Some questions might be personal or make you feel uncomfortable. You may refuse to answer any question(s) you do not wish to answer.

Health Information:

• As with all research, there is a chance that confidentiality could be compromised; however, we take precautions to minimize this risk.

Benefits Of Participating In The Study

You won’t benefit from taking part in this research study. It is for the benefit of research. Others with endometrial cancer (EC) may benefit in the future from what we learn in this research study. The study goal is to develop a minimally invasive detection test for EC to decrease pain associated with endometrial sampling, improve early access to early diagnosis and to reduce disparities in EC.

Participation Is Voluntary

Taking part in research is your decision. Take your time to decide. Feel free to discuss the study with your family, friends, and healthcare provider before you make your decision. Taking part in this study is completely voluntary and you do not have to participate.

To learn more contact the OBGYN Clinical Research Office at (507) 422-1892.