Gastroenterology & GI Surgery

Welcome to the Mayo Clinic Gastroenterology & GI Surgery Page! With one of the largest group of digestive disease specialists in the world, Mayo Clinic has been recognized as the nation's best Gastroenterology & GI Surgery hospital by U.S. News & World Report. Follow the page to learn about clinical trials and up-to-date research, and find resources for all your gastroenterology needs. Our goal is to connect you to others, and become informed decision makers; so post a comment, share your story, own your health.

May 30, 2017

The Gluten ELISA Test Kit

By Kanaaz Pereira, Connect Moderator, @kanaazpereira

If you have celiac disease, you may rely on commercial test kits for detecting gluten in food. But how reliable are these test kits for gluten detection? Dr. Joseph Murray, M.D., evaluates the ELISA test kits, based upon a study published in Cereal Chemistry.

The team of researchers who set out to evaluate the accuracy of 14 ELISA kits for gluten detection found that none of the currently available ELISA methods can accurately detect and quantify gluten in all cases. In the face of these results, Dr. Murray has the following recommendations for individuals who use the kits:

  • The FDA allows food products containing less than 20 parts per million of gluten to be labeled as gluten-free.
  • Be very cautious, and repeat the test multiple times.
  • Pay attention to the quality of the test.
  • Make sure that the test is appropriate for the matrix of the food type.

The authors of this study conclude that further improvements are urgently needed, and recommend focusing on competitive formats, improving extraction methods, and the detection of relevant gluten peptides.

Read the full study online here.

For more information about celiac disease, visit disease.

Dr. Murray is a gastroenterologist and celiac disease expert at Mayo Clinic.

Please login or register to post a reply.

Invite Others

Send an email to invite people you know to join the Gastroenterology & GI Surgery page.

We'll include this text in the user's invitation.