IgG4-RD or immunoglobulin G4-related disease can affect almost any organ in the body. It’s manifestation is most often seen in the pancreas – autoimmune pancreatitis – or in the bile ducts and liver, where it is known as IgG4-related sclerosing cholangitis or IgG4-associated cholangitis.
The dramatic response to steroids makes autoimmune pancreatitis (AIP) unique among pancreatic disorders, but many cases are steroid-resistant, and relapse is common after steroid withdrawal. Mayo Clinic gastroenterologist, Dr. Mark Topazian discusses a recent study which shows that rituximab maintenance therapy can prolong remission.
So what are some "take home” messages from this study?
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