Autoimmune enteropathy is a rare disorder in which the immune system causes damage to the lining of the intestines. Symptoms of autoimmune enteropathy (AIE) can be very debilitating, including severe diarrhea with malabsorption and weight loss – symptoms that mimic refractory celiac disease – but AIE does not respond to any dietary modification such as a gluten-free diet.
Mayo Clinic gastroenterologist, Dr. Joseph Murray, explains the results of a study, published in the journal of Clinical Gastroenterology and Hepatology, which investigated the clinical and histologic features of adults with AIE compared to adults with refractory celiac disease.
The study concluded that budesonide may be a potential candidate for initial treatment of AIE to induce remission and with a safe therapeutic profile used for long-term maintenance therapy.
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