Hello @k245888, welcome to Connect. I'd like to introduce a few members who have talked about osteomyelitis here on Connect, albeit different areas of the body. @konniehoover, @carole1, @pmaze2663 have all discussed osteomyelitis on Connect in the past and I am inviting them back to Connect to share their experiences with treatment and management.
@k245888, you mention that you have already had two debridements along with 2 PICC lines with antibiotics that have been unsuccessful. If you are comfortable sharing, has your provider identified the type of bacteria/germ that has infected your bones? Here is what Mayo Clinic has to say as far as treatment for myelitis, https://www.mayoclinic.org/diseases-conditions/osteomyelitis/diagnosis-treatment/drc-20375917, which sounds similar to the path your current provider has taken.