About

Member has chosen to not make this information public.

Groups

Member not yet following any Groups.

Pages

Member not yet following any Pages.

Posts (47)

Jun 7, 2017 · Melanoma: genetics and recurrence in Cancer

This was the biopsy report back in 2000 Diagnosis: Malignant Melanoma. Clark’s Level 3. Tumor Thickness 1.45mm. The Margins of Excision appear uninvolved. Suggest re-incision.
I did have a chest X ray during that time and a CT scan. They seldom use Clark’s level anymore as a measurement. http://www.skincancer.org/skin-cancer-information/melanoma/the-stages-of-melanoma/guide-to-staging-melanoma

Jun 7, 2017 · Melanoma: genetics and recurrence in Cancer

you are correct about it being the most common, however it can be highly aggressive…Eric Sizemore was the first warrior I knew that had it…you can see some of his videos at the following. I am not certain what stage they are approving for Yervoy but some changes have recently taking place regarding immunotherapy. They used to make folks wait until Stage 3 but they have realized that this was too late. You may be able to check it out at ASCO in the abstracts http://am.asco.org/daily-news or through some of the clinical trials at Cancer.gov Eric had superficial spreading and it is the thing nightmares are made of. @ https://www.youtube.com/watch?v=89_O6ybm8-g&t=124s

Jun 7, 2017 · Melanoma: genetics and recurrence in Cancer

I am a Stage 4 melanoma survivor…I had it removed the first time from my neck in 1991. It came back in same place in early 1995. I waited to have it removed because my son who was then 14 had been dx’ed with a rare and deadly small cell sarcoma and died when he was 16 in 1998. I finally went and had it removed from my neck again in 2000 and returned a couple months later to have 5 SLN removed 9 early 2001). They were all clear. Jump ahead to 2009…I had been complaining for months and months something was wrong but no one seemed to listen. In June 2009 I was dx’ed Stage 4 Metastatic melanoma and it was in the lymph nodes and pressing against my superior vena cava. they said nothing could be done back then…but despite the prognosis of 6 months I went on to find my own treatments…I have been NED ( no evidence of disease). Superficial spreading is a horse of another color and highly recommend you ask about immunotherapy …perhaps Opdivo …those friends of mine who had it are no longer here. Didn’t say that to scare you…but to tell you that there are treatments now available to you that they never had. Yervoy is 4 infusions and it has been approved already…Opdivo may not be approved yet as a prevention…would not recommend Interferon or Leukine injections …they don’t do much as a stand alone treatment and IF they did anything they might postpone recurrence for a short time…nothing more

May 4, 2017 · Chest pain conflicting diagnosis in Heart & Blood Health

I am having some of these issues. I also go to Mayo. I had my surgery back in 2015 Dec. Recently I have been so tired…having odd pains, tightness in my chest, shortness of breath,pain in my arm pit, pain in my left shoulder going down to my fingers and they become achy and numb. I have racing heart sometimes as I lay down in bed and takes awhile to breath normally. I have been having problems with my left eye losing vision as a dark curtain comes across it, but lasting only a minute or two. It doesn’t matter if I am driving, or sitting in a chair or standing- I even have some fevers, chills, and going thru sweats. My sternum and chest wall is sensitive .I had a hysterectomy when I was 35 and have my ovaries, thoracotomy to to take out some lymph nodes as I had stage 4 melanoma in 2010 ( cancer free after immunotherapy) Last infusion was 2013. I remain cancer free. I had a myectomy and repair of aortic stenosis and kept all of my valves…Dr Schaff removed the scar tissue on my aorta in Dec 2015. I have been going through a battery of tests since last Friday..So far my scans show everything is basically working great…I do have slight leakage of the aortic valve but nothing to worry about. My labs look basically fine except NT-proBNP,s is 657 pg/mL up about 150 from presurgery labs from 2015. My platelets are low, but they have been low for years since I was in cancer treatment. Echo is fine…MRI appears fine…I had a 48 hr halter and the Dr didn’t comment. He is running cultures to see if there is a bacteria…but all my blood work appears within the normal range…even my white count….So all I have left to wait on are the cultures and an eye app’t with an ophthalmologist. I am beginning to feel like a hypochondriac…I don’t know whats wrong with me

Nov 2, 2016 · Video Q&A about Hypertrophic Cardiomyopathy & Surgical Treatment Apical Myectomy in Hypertrophic Cardiomyopathy (HCM)

On December 10, 2015, Dr. Schaff performed:
1. Membranectomy.
2. Septal myectomy.
Final dx was Membranous and tunnel subaortic stenosis. Will this grow back?

Nov 2, 2016 · Video Q&A about Hypertrophic Cardiomyopathy & Surgical Treatment Apical Myectomy in Hypertrophic Cardiomyopathy (HCM)

Dr Schaff did my surgery in mid December…doing fine, no limitations. On 10 MG metoprolol twice a day now…:)

Sep 20, 2016 · Stage 4 Malignant Melanoma internal in Cancer

They have basically moved away ( at least for now) conventional chemotherapy and are now using targeted drugs like the B-raf and MEK inhibitors and Immunotherapy drugs like Ipilimumab ( yervoy) Nivolumab (opdivo) and Keytruda…they basically take off the brakes and kick up the immune system ( the opposite of chemo which kills fast growing cells, good and bad ones) . IL-2, interferon were the oldest drugs approved by the FDA for melanoma. Leukine is different in that it is a man-made protein that stimulates the growth of white blood cells in your body. Interferon is also a group of proteins known as cytokines, molecules used for communication between cells to trigger the protective defenses-they are found in the body and also man made…they don’t do much for melanoma but do have some nasty side effects. Ipilimumab ( yervoy) Nivolumab (opdivo) and Keytruda are considered the gold star of melanoma treatments now. They are also doing TIL therapy but it is more complicated and does not have as high of response rate as Nivolumab or Keytruda.