I was on amiodarone. It was giving me constant headaches. The doctor switched me to multaq. It does not give me headaches and seems to work as well or better. The half-life of amiodarone is about 58 days, so it will take a long time for it to get our of one’s system. After my heart problems I didn’t care to eat and had a difficult time maintaining my weight. Doctor put me on anxiety pill (mirtazapine) which takes 2 to 4 weeks to fully work; my appetitie has picked up and I almost eat too much. Your mother has a lot of issues going on and I wish you and her the best.