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2 days ago · New study highlights the importance of genetics research

An exciting paper was recently published in Nature Genetics titled “The complex genetics of hypoplastic left heart syndrome”.  This elegant study was led by a research team at the University of Pittsburgh School of Medicine and highlights the creation of the first mouse models of hypoplastic left heart syndrome [...]

Mon, May 15 12:39pm · Share the Science: Strengthening the HLHS Heart with Cord Blood

Join Dr. Nelson, director of the Todd and Karen Wanek Family Program for HLHS, this Wednesday, May 17 at 2 p.m. CT to learn more about using umbilical cord blood stem cells to potentially strengthen the heart. The free webinar is hosted by [...]

Fri, May 5 10:26am · Mayo Clinic’s Fontan procedure study shows improvement in survival rates

Mayo Clinic recently published the largest single center study on the outcomes of the Fontan procedure. The goal of the study was to determine how well patients were doing 10, 20 and 30 years after a Fontan procedure at Mayo Clinic. The most promising result from the study shows [...]

Aug 18, 2013 · Stem Cell Based Clinical Trial for HLHS

The Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome at Mayo Clinic takes another step toward its goal of delaying or preventing heart transplant for people affected with Hypoplastic Left Heart Syndrome, with the announcement of a stem [...]

Mar 21, 2013 · The Goals of the Imaging and Outcomes Component of the HLHS Research Program

In HLHS, the right ventricle (RV) is the only cardiac pump and the geometric shape of the right ventricle is vastly different from that of the left. This difference makes consistent and accurate functional assessment of the RV and its ejection fraction in HLHS patients is a challenge. Our objective [...]

Mon, Apr 17 8:59am · Congratulations to the 2017 IMPACT Winners!

On March 18, the Innovative Minds Partnering to Advance Curative Therapies (IMPACT) program engaged over 200 undergraduate students from 23 different Minnesota colleges. IMPACT is a competitive program open to Minnesota undergraduate students that encourages them to submit hypotheses for different challenges. It is sponsored by [...]

Mon, Apr 10 9:52am · Dr. Nelson featured on "Heart to Heart with Anna"

Dr. Nelson was recently featured on the radio show “Heart to Heart with Anna” to discuss the work our program is doing to delay and prevent heart failure for individuals with HLHS. Dr. Nelson and Anna discuss the clinical trial using umbilical cord blood as well as the clinical trial [...]

Jan 27, 2016 · How Studying Genes Helps Us to Understand HLHS

Here at the Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS), we are working on new ways to delay and prevent heart failure for people with congenital heart defects. In order to do that, we are studying regenerative (stem cells) therapies, genetics and imaging [...]

Mon, Mar 13 9:14am · Mayo Clinic to host undergraduate students at IMPACT Symposium on March 18

The Innovative Minds Partnering to Advance Curative Therapies (IMPACT) Program at Mayo Clinic will hold their fourth annual IMPACT Symposium this Saturday, March 18 from 9:00 a.m. until 5:00 p.m. at Mayo Clinic in Rochester, Minnesota. The IMPACT Symposium is a daylong conference for students to pitch their [...]

Jul 21, 2016 · New Clinical Trial Using Bone Marrow Stem Cells

The Todd and Karen Wanek Family Program for Hypoplastic Left Heart Syndrome (HLHS) is excited to announce a new clinical trial for children and adults with single right ventricles. This clinical trial uses stem cells obtained from a person’s bone marrow and delivers them into the heart muscle [...]