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May 21, 2015 · Webinar: What Women Need to Know about Ovarian Cancer in Gynecologic Cancers

In a postmenopausal woman, ovarian masses are usually a growth of some sort—could be benign, could be cancer, could be something in between called a borderline tumor. Imaging and tumor markers may not be enough to rule out a cancer as cancers and benign tumors can look the same on imaging. And there is a small proportion of ovarian cancers that have a normal CA125 level. Further evaluation in the setting of an ovarian mass and pain is warranted. If you would like to be evaluated at Mayo Clinic, you may make an appointment by calling: 507-284-4137.

May 19, 2015 · Webinar: What Women Need to Know about Ovarian Cancer in Gynecologic Cancers

Yes, international patients are eligible to participate. However, I would suggest you consider staying in the US rather than trying to travel back and forth. In addition, you should have complete records submitted with your “new patient registration” with a specific question to the Medical Oncology team to review candidacy for clinical trials prior to making an appointment. This could save you the potential problem of being disqualified based on prior treatments or other criteria.

May 19, 2015 · Webinar: What Women Need to Know about Ovarian Cancer in Gynecologic Cancers

Yes, we currently do not distinguish between the different subtypes of ovarian cancer and use the same general platinum-taxane doublet therapy (for instance cisplatin or carboplatin plus paclitaxel or Taxotere) for all subtypes.

May 19, 2015 · Webinar: What Women Need to Know about Ovarian Cancer in Gynecologic Cancers

There are many potential therapies for recurrent ovarian cancer and the pros/cons should be discussed with your local oncologist. It is difficult to give advice about what treatments to do now or next without having more information about your medical history, tolerability of prior chemo, life goals, physical condition, etc. The best way to answer this question is through a face-to-face consult or electronic consult if your physician is part of the Mayo Clinic Network.

May 19, 2015 · Webinar: What Women Need to Know about Ovarian Cancer in Gynecologic Cancers

Many types of tumors develop mutations in genes over time. Most often these mutations or alterations in tumors are not inherited. Encourage you to discuss results with your oncologist.

May 19, 2015 · Webinar: What Women Need to Know about Ovarian Cancer in Gynecologic Cancers

You should not have to do any type of screening or preventative measures if you do not have the mutation identified for your mother.

May 19, 2015 · Webinar: What Women Need to Know about Ovarian Cancer in Gynecologic Cancers

There are other genes, aside from BRCA1 and BRCA2, that may have been associated with your ovarian cancer. Would recommend revisiting with a genetic counselor to discuss whether additional genetic testing is warranted. If you have one of the less common genes that has been implicated in ovarian cancer, your sister’s risk could be elevated above the general population risk.

May 19, 2015 · Webinar: What Women Need to Know about Ovarian Cancer in Gynecologic Cancers

Recommend discussing personal and family history with genetics professional to assess risk for Lynch syndrome