I have just joined in this discussion. I forgot to get my refill and went either 2 or 3 days without. Oh how bad that is!!! I did get the refill today and will see my doctor tomorrow, as I really want to get her permission and instructions on tapering off. I tried once before and had all of this swimming head and such. The past couple of days I seem to have lost some bladder control. Only some. Has anyone experienced this symptom as they went off of Pristiq? Thanks for any response.