Went to the urologist today for an IC treatment and asked questions about Anastrozole. It seems that if you had Cancer and are older it blocks estrogen. And since I am 72, had a hysterectomy, plus cancer that was estrogen receptive the bladder discomfort could last forever. I asked the urologist if this herbal suppository, Revaree, can be used by me. It did help with itching and burning. She said yes I could. The Company is Bonafide.