Yes, the irritated skin can be very sore and lesions are so hard to heal. I have tried many different things and found nothing that really does the job. The less leakage you have the less irritation. The skin gets irritated from the stool and if you have found equipment that lasts you for 3 – 4 days. I say Bravo! I consider myself lucky if I go two. If I get two nights in a row, I don't wait for a leak or a fail, I just go ahead and change it. My motto is "It's easier to change than to clean up a mess". I use Hollister equipment ad I use a barrier ring. Each person must find their best combination.