So I was on amitriptyline 50 mg for 14 years for pain. I tried to get off but couldn't hack it. I was taking care of my new granddaughter and it was too much. So my doc switched me to Pristiq (desvenlafaxine) 25 mg for one month than 50mg for one month, so I have been off the amitriptyline for 2 months now. Doc claims I am over withdrawal from that drug. But I felt worse than ever, severe headache, on the pristiq etc. (horrible drug) so after 2 months I'm trying to clear the pristiq and rid my body of antidepressants. Have gone down to 25mg now for one week. Not feeling great, but better than on the 50. Wondering what your take is on getting off this drug. No brain zaps yet.