I had a problem with C. Diff a few years ago. It seemed every time I finished the medical treatments it would come back. They had me do Flagyl a few times and they had me try Vanco but it always came back. I ended up doing a natural treatment that I read about and I have been 3 years C. Diff free. This is what the article said to try and I followed it….. Primadophilus Optima by Nature's Way (contains 35 billion CFUs per capule) 1 capsule twice a day for 1 month then 1 capsule once a day for 2 more months, N-acetylcysteine (NAC) 600 mg 3 times a day between meals for 3 months, Deglycyrizinated Licorice (DGL) Chew 2 tablets (760 mg) 20 minutes before each meal for 3 months, Garlic Extract (I used Kyolic Reserve Aged Garlic Extract) 1 tablet (600 mg) twice a day with meals for 3 months. I have been c. dif free for 3 years. It may be worth a try for those of you that seem not to be able to shake it.