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Mon, Apr 29 1:11pm · Concerned about the side effects of anastrozole in Breast Cancer

Wow! This study is really interesting. Summation: Interpretation
Aromatase inhibitors reduce recurrence rates by about 30% (proportionately) compared with tamoxifen while treatments differ, but not thereafter. 5 years of an aromatase inhibitor reduces 10-year breast cancer mortality rates by about 15% compared with 5 years of tamoxifen, hence by about 40% (proportionately) compared with no endocrine treatment.

Sun, Apr 28 8:53pm · Concerned about the side effects of anastrozole in Breast Cancer

This is very interesting article – but written in 2013. I wonder if they have any more recent data – I'll ask my oncologist. But I don't see her until July.

Sun, Apr 28 12:55pm · Concerned about the side effects of anastrozole in Breast Cancer

It is vital you trust your doctor – I would not hesitate to find a new one if my oncologist said that to me. Hang in there. Guess they are not good friends any longer!

Sat, Apr 27 8:07am · Concerned about the side effects of anastrozole in Breast Cancer

75% of patients have no side effects or they are mild enough that they take it for 5 yrs. 25% stop within the first 2 years from the side effects. I do know it can raise your blood pressure. Talk to your oncologist about your concerns. I'm going for the 5 years. Mainly it dries out your everything: hair, skin, eyes. I've have mild hair loss, and the joint pain (in my hands too!) so far it's all manageable. Radiation was okay for me too – just like a sunburn & some fatigue. Hang in there.

Fri, Apr 26 2:38pm · Concerned about the side effects of anastrozole in Breast Cancer

Google this, I found this: Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women. … Type II aromatase inhibitors such as anastrozole and letrozole, by contrast, are not steroids and work by interfering with the aromatase's heme. There's a lot of info out there on this.

Fri, Apr 26 2:33pm · Concerned about the side effects of anastrozole in Breast Cancer

I'm not familiar with that steroid – but in general, steroids fight inflammation and should only be taken for a short period of time. Long term steroids in general have BAD long term side effects. I've been given it (shots and pills) for asthma & allergies. You need to ask your oncologist about this and any long term effects. I'm guessing there are many different types of steroids some are a form of hormones.

My Grandma in the 1940's was given massive steroid doses for her arthritis when they had not idea of the long term effects – she ended up with Cushings syndrome and subsequently passed at 59. Her massive doses contributed to her death. My dad was terminal with pulmonary fibrosis – they gave him massive doses, but they were just trying to keep him alive & not concerned with the long term side effects.

Fri, Apr 26 2:24pm · Concerned about the side effects of anastrozole in Breast Cancer

They have me down for a Digital tomosynthesis a 3-dimensional picture of the breast using X-rays. from Google: Digital tomosynthesis is a new kind of test that's trying to overcome these three big issues. It takes multiple X-ray pictures of each breast from many angles. The breast is positioned the same way it is in a conventional mammogram, but only a little pressure is applied — just enough to keep the breast in a stable position during the procedure. The X-ray tube moves in an arc around the breast while 11 images are taken during a 7-second examination. Then the information is sent to a computer, where it is assembled to produce clear, highly focused 3-dimensional images throughout the breast.

Early results with digital tomosynthesis are promising. Researchers believe that this new breast imaging technique will make breast cancers easier to see in dense breast tissue and will make breast screening more comfortable.

I'll let you know if it's more comfortable or not!

Fri, Apr 26 2:20pm · Concerned about the side effects of anastrozole in Breast Cancer

Thanks so much for this info!! It helps to put it all in perspective.