Thanks for your response and you are correct, those symptoms I described are related to long term back issues; stenosis, spondylolisthesis and scoliosis, for which I had back surgery in 2010. I'm determined not to have another back surgery if at all possible. I also have a neuromuscular disease called CMT (Charco, Marie, Tooth) and some PN, both of which have resulted in muscle atrophy in my legs and balance problems which is why I wear leg braces. I was wondering if the PEA and Fibro Cream might help some of my overall pain. I guess I'll just wait until I've been to Mayo at the end of October and see what they say about my complex condition.