Just updating my experience with tapering from 75 mg Effexor after taking it for over 15 years. I have taken 3 months to get down to 18.5 mg every other day. I tried reducing faster but experienced more zaps, nausea, etc., so I began tapering more slowly from 75 mg to 37.5 to 18.5 daily to now 18.5 every other day. I have found that CBD oil does help. 3 drops sublingually twice daily seems to work for me. I still get occasional sharp head pains that last a few seconds, some nausea, and even constipation (not sure how much of that is related to venlafaxine). My psychiatrist did put me on 150 mg Wellbutrin XR when I started withdrawal from Effexor, and I believe that prevented me from relapsing into depression. I am trying to be very patient as the very gradual withdrawal has helped minimize the side effects of withdrawal from Effexor. Optimistically, I hope to be Effexor free within 3 months.