I have been taking anastrozole for 2.5 years now, and it is not clear to me what is a side effect and what is just aging. I suppose the minor hot flashes are a side effect, but ice water takes care of that. I have increased back pain and difficulty sleeping, but these existed to a lesser extent before I started the drug. I am waiting for the results of a bone density test.
My cousin took this drug 20 years ago with no problems, and her friend accidentally took for 10 years (misunderstood how long she was supposed to take it) and she had no issues with it. So, it appears from reading all the responses on here, that reactions are certainly highly personalized! I hope we all get through all this cancer and therapy and live long healthy lives!