Thankyou for your reply. To answer the questions you raise, we were given no answers. She has had high blood pressure, but nothing as dramatic as this and was taking medication for it. Her doctor ( general Practitioner ) and her Oncologist said they didnt believe there was anything more that could be done. And the fact that she had no fever at that time seemed to show that she had no infection. My reply to that is that we are dealing with a lady with a very compromised immune system because of the MS. Maybe her body was not responding as it should to infection. Now that she is back on antibiotics, maybe she will improve somewhat. Im under no false illusion that my Mom will be running a marathon any time soon. I know the MS has scarred her brain and its terminal. Its just odd that Dec 31, I had a lengthy talk with her and 8 hours later shes having seizures. She and my Dad live by themselves and my father didnt realize that the constant need to urinate…. with little output… means she had a bladder infection. We are not sure then how long she had the initial infection, but probably better than a month. The biggest problem for my mom to see a specialist is that they will not come see her in the rehab center. So its a very disruptive, lengthy process to get her in a wheelchair and load her in a van and drive her around, just for them to say they cant do any more. If she rebounds from this fever, you can bet I will be so much more insistent on finding the cause of her current condition.