I had taken fosamax and other drugs for years and finally did the Forteo for two years. I was very happy to have some gain. The doctor I had gave me another fosamax type drug to help maintain what I had gained. He moved to another state and his replacement immediately took me off any osteoporosis drugs because I had been on them so long. After several months I went to an Endocronologist because I kept feeling an internal nudge to do so. I have lost a lot of what I had gained and am now at a scary -4. She highly recommended Prolia which I am going to start as soon as possible. I do have a tooth to be extracted and may have to wait a bit after that. I would definitely try the Forteo. I had no reations to it at all.