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@jeffmarc thanks for the information. I read somewhere in these comments that Orgovyx loses its effectiveness...

https://connect.mayoclinic.org/comment/1480032/

Discussion: Can a short term of taking Orgovyx cause leg pain and weight gain?

Support Group: Prostate Cancer

Posted: Jan 11 7:48pm

I'm at six months on Orgovyx and I've had every side effect listed on the Orgovyx...

https://connect.mayoclinic.org/comment/1305684/

Discussion: Orgovyx side effects and handling them

Support Group: Prostate Cancer

Posted: May 16, 2025

FWIW, if you have to go on ADT I would choose an LRNH antagonist over an...

https://connect.mayoclinic.org/comment/1193736/

Discussion: Surgery? Radiation? Can I have an independent suggestion?

Support Group: Prostate Cancer

Posted: Dec 19, 2024

We live in Germany. My husband started Orgovyx today and will be on it for 12...

https://connect.mayoclinic.org/comment/1526766/

Discussion: Optimal Duration of Hormone Therapy

Support Group: Prostate Cancer

Posted: Mar 14 12:08pm

@oldgreenpaint I used to get Lupron Shots every six months. A drug that works just like...

https://connect.mayoclinic.org/comment/1533926/

Discussion: We need others' info on Stage 4 prostate cancer.

Support Group: Prostate Cancer

Posted: Mar 23 9:54pm

I am on orgovyx 15 months now. Psa fell to undetectable in 3wks or less. Also...

https://connect.mayoclinic.org/comment/1065882/

Discussion: Will Orgovyx (relugolix) Reduce Prostate Cancer without Radiation?

Support Group: Prostate Cancer

Posted: May 11, 2024

I am on week 11 of Orgovyx. You are correct in that the recovery once therapy...

https://connect.mayoclinic.org/comment/1014867/

Discussion: Radiation + ADT

Support Group: Prostate Cancer

Posted: Feb 13, 2024

It will work. Avoid the next one. Get Orgovyx, or if your insurance company is delaying...

https://connect.mayoclinic.org/comment/1366029/

Discussion: Started Hormone Therapy Today

Support Group: Prostate Cancer

Posted: Aug 7, 2025

@jaacm1 You mentioned you have manageable incontinence and ED. I also have these issues following RP...

https://connect.mayoclinic.org/comment/1330234/

Discussion: Salvage radiation decision: with or without hormone therapy?

Support Group: Prostate Cancer

Posted: Jun 18, 2025

Hi, I started Orgovyx about 2 weeks ago and I am starting to experience night sweats....

https://connect.mayoclinic.org/comment/1030833/

Discussion: What's your experience with Orgovyx (relugolix)?

Support Group: Prostate Cancer

Posted: Mar 10, 2024

Layman opinion: Stay with the devil you know. I took Orgovyx for 4 mos as part...

https://connect.mayoclinic.org/comment/993634/

Discussion: How long do Lupron side effects last after treatment concludes?

Support Group: Prostate Cancer

Posted: Jan 8, 2024

My oncologist recommended that I get a depo-provera shot a year after I suffered from constant...

https://connect.mayoclinic.org/comment/1461486/

Discussion: Menopause products for hot flashes from Lupron

Support Group: Prostate Cancer

Posted: Dec 15, 2025

There must have been some cancer cells left after prostatectomy, and then was not totally irradiated...

https://connect.mayoclinic.org/comment/1293105/

Discussion: What's your experience with Orgovyx (relugolix)?

Support Group: Prostate Cancer

Posted: Apr 29, 2025

I have been on first and second generation ADT for three months. The first month was...

https://connect.mayoclinic.org/comment/1112958/

Discussion: How to decide what next for ADT?

Support Group: Prostate Cancer

Posted: Jul 27, 2024

@jeffmarc wrote "I am on Orgovyx because it is cheaper than Lupron where I get treated."...

https://connect.mayoclinic.org/comment/1414689/

Discussion: Doublet Therapy Holiday - Option for Oligorecurrent Prostate Cancer?

Support Group: Prostate Cancer

Posted: Oct 13, 2025

I just started ORGOVYX for less than week. Although moderate ethanol consumption may be tolerated I...

https://connect.mayoclinic.org/comment/1263988/

Discussion: Got some answers for stage 4 prostate cancer

Support Group: Prostate Cancer

Posted: Mar 22, 2025

So everyone on Medicare or Advantage plan is paying $8000 a yr to take Orgovyx? That's...

https://connect.mayoclinic.org/comment/1027407/

Discussion: What's your experience with Orgovyx (relugolix)?

Support Group: Prostate Cancer

Posted: Mar 4, 2024

I have to add, that I had two bowel preps within two weeks while on Orgovyx...

https://connect.mayoclinic.org/comment/1471277/

Discussion: Having a colonoscopy next week, can I still take Orgovyx?

Support Group: Prostate Cancer

Posted: Dec 31, 2025

Jeff, I break into a sweat every time I watch the news - and I’ve been...

https://connect.mayoclinic.org/comment/1349686/

Discussion: Hormone Treatment Experience

Support Group: Prostate Cancer

Posted: Jul 16, 2025

Don’t know of it…but have you considered Orgovyx? I only took it for 6 months but...

https://connect.mayoclinic.org/comment/1313093/

Discussion: For Newly Arrived Bros: A Day In The Life With ADT

Support Group: Prostate Cancer

Posted: May 26, 2025

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