What's the next step after breast cancer operation?

Posted by nina995 @nina995, Oct 19, 2022

Breast cancer in situ has been slightly infiltrated, and unilateral total breast incision has been performed. Is chemotherapy and targeted treatment necessary in later treatment? Doctors in mainland China have different opinions. My friends are worried that if they do it: 1) Side effects affect the quality of life 2) Drug resistance. In case of recurrence, no better drugs can be used.

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Are your doctors doing an Oncotype Dx test to help determine whether chemo is of benefit? Is your tumor HER2 negative and estrogen positive? Many of us don't have chemo, even for grade 3: the Oncotype and other similar tests have helped patients avoid chemo in many instances.

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@windyshores

Are your doctors doing an Oncotype Dx test to help determine whether chemo is of benefit? Is your tumor HER2 negative and estrogen positive? Many of us don't have chemo, even for grade 3: the Oncotype and other similar tests have helped patients avoid chemo in many instances.

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Yes, she did the test.
her2 positive

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Hello, Anyone in here can advise what treatment need to do? Chemo + Herceptin ? Any other suggestion?

Current situation and test results as below —
1 Breast ductal carcinoma in situ with micro-invasion
2 ER/PR Negative
3 HER2 strong positive
4 mastectomy has been performed
5 No lymph node metastasis
6 Her2 is in situ cancer, not in FIC

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@nina995

Hello, Anyone in here can advise what treatment need to do? Chemo + Herceptin ? Any other suggestion?

Current situation and test results as below —
1 Breast ductal carcinoma in situ with micro-invasion
2 ER/PR Negative
3 HER2 strong positive
4 mastectomy has been performed
5 No lymph node metastasis
6 Her2 is in situ cancer, not in FIC

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What grade?

I initially had a positive HER2 test from biopsy, but after surgery, it was equivocal and then with further testing, negative. I was told that the DCIS part of my cancer was more likely to be positive.

I think it really helps to get a second or even third opinion. My second opinion MS commented on how well she knew my first opinion doc, so I got a third opinion! There may also be a tumor board that can give their recommendation.

Especially with a mastectomy done (any radiation?) there may be options. I really don't know. But I would ask doctors what your options are and what they recommend, and hearing it from more than one doc can help you feel committed to your treatment and/or feel reassured about your choice.

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My next step would be to get my oncologist's recommendations and then get a second opinion from a different oncologist.

We are all patients here, or friends or family of patients, not doctors ourselves. We just share our experiences and any knowledge gained therefrom but are limited by what we've learned and medical science is ever-evolving and doctors opinions can vary widely too. You could start with what your oncologist(s) recommend and narrow down your research further once you know what's being actually recommended.

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@nina995 this is a pretty complicated question. There are a lot of factors involved in making the best decision. The her2+ test does add a different level of conversation about chemo. There is a conversation where you can connect with some her2+ patients. Her2+ anyone else;
https://connect.mayoclinic.org/discussion/her2-positive/
Is your friend Pershing treatment in mainland China?

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@auntieoakley

@nina995 this is a pretty complicated question. There are a lot of factors involved in making the best decision. The her2+ test does add a different level of conversation about chemo. There is a conversation where you can connect with some her2+ patients. Her2+ anyone else;
https://connect.mayoclinic.org/discussion/her2-positive/
Is your friend Pershing treatment in mainland China?

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HER2+ makes things more complicated. I had a mistaken diagnosis of HER2+ from biopsy, and had already bought a wig for chemo hair loss, when the post-surgical tests came back HER2-.

Your results were apparently after surgery, so more reliable. There are special meds for HER2 in addition to chemo. Talk to your doc and if you need to, another doc. It helps to get opinions. Treatment feels more tolerable, I think, when you are sure about it and are committed. Good luck!

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@windyshores

HER2+ makes things more complicated. I had a mistaken diagnosis of HER2+ from biopsy, and had already bought a wig for chemo hair loss, when the post-surgical tests came back HER2-.

Your results were apparently after surgery, so more reliable. There are special meds for HER2 in addition to chemo. Talk to your doc and if you need to, another doc. It helps to get opinions. Treatment feels more tolerable, I think, when you are sure about it and are committed. Good luck!

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Hello,
I am HER2 + grade 3. After surgery 3/22. Cancer clear, preventative treatment plan
25 rounds of radiation done.
2 rounds of herceptin and moved to T-DM1 for 14 rounds after tumor board reviewed lymph nodes removed.
So - herceptin very easy and no side affects for me. I understand and agree with my treatment plan. Even after the switch to T-DM1.
For a longer part of my life.
I don’t give advice, but HER2 is aggressive and even cancer free, I will focus on science for No reoccurrence!! I would go with herceptin for all rounds then consider alternative medicine you describe “china”
Stay with science and herceptin if this is your treatment plan.
Preventative is important!

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@boathouse

Hello,
I am HER2 + grade 3. After surgery 3/22. Cancer clear, preventative treatment plan
25 rounds of radiation done.
2 rounds of herceptin and moved to T-DM1 for 14 rounds after tumor board reviewed lymph nodes removed.
So - herceptin very easy and no side affects for me. I understand and agree with my treatment plan. Even after the switch to T-DM1.
For a longer part of my life.
I don’t give advice, but HER2 is aggressive and even cancer free, I will focus on science for No reoccurrence!! I would go with herceptin for all rounds then consider alternative medicine you describe “china”
Stay with science and herceptin if this is your treatment plan.
Preventative is important!

Jump to this post

You are a force of nature!! I am so happy to hear after all that you went through, that you are cancer free and doing well. Thank you for chiming in and helping others. My journey with her2+ is much different, and still very much the same, but with a lot of older science involved. We have come a long way since my journey started.
You rock❣️

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