What is best time of day to take Forteo?

I have read ppl take FORTEO at either time. Injecting at bedtime is a good way to feel less of the potential side effects at the beginning months. Then there are ppl think injecting in the morning will help monitoring any potential side effects. Some even think morning dosing may have a bigger impact on bmd improvement, which I haven't read a solid study proving this. Bone pain is not a common side effect of FORTEO, is it?

How long did you take fosamax before the start of FORTEO, @rogerscott8562, if you don't mind sharing that info? Are you and your endo checking bone turnover markers for your FORTEO therapy?

I took Alendronate for about 45 days before taking FORTEO. I just finished my second month of Forteo. Markers and DEXA scan will come after 3 months of Forteo. McCormick mentions bone pain as a side affect in his book, Great Bones.
The medication guide lists pain, joint ache and nausea as common side effects. The did not get much pain in the first month.
My GP prescribed Alendronate. Upon reading Great Bones, I found that prescription unacceptable for a -4.5 T-score. I needed a stronger drug to avoid high risk of fractures for the rest of my life. As this discussion group shows there are a lot of ignorant doctors that can and do harm to patients. My specialist is doing everything right.

Prescribing information and post market experiences do not specify bone pain as a common side effect, from what I read. However, pain experienced as headache is more common. If bone pain persists or becomes bothersome, you might want to consult your endo. In theory, there shouldn’t be a drawback with timing of FORTEO injection, especially in regard to its anabolic effect. Maybe @gently have a different take? Endogenous PTH secretion is tightly regulated by blood free calcium level, without a circadian pattern. Basically our body has a mini or nano pulsing of PTH at any given time depending mainly on blood calcium level, and this regulated secretion of PTH maintains our bone health. A daily injection of FORTEO, essentially is a large daily pulsing or bonus of PTH analog. It is this pulsing that results in its anabolic effect. A genius invention.

It’s great that you started an anabolic. Your brief use of fosamax is unlikely to affect FORTEO too much. Do you have a baseline of CTX/p1np tested, before the start of FORTEO? It is interesting that you will have a Dexa scan at 3mo of FORTEO. May I ask why so early?

Roger bone pain was not signaled in premarket trials. Aftermarket it is reported commonly. Vasodilation begins with the injection peaking at around 2hours diminishing at around 4hours. Your timing gives rise to the suspicion that you are feeling vasodilation. Some effect may be mitigated by a salt snack, being well hydrated and exercise.
I've heard physicians say that the pain is your bones growing. I have doubts in that regard. Often what we feel in the muscles close to the bone seem to be bone pain. But either way you might try the injection earlier in the day. Muscles benefit from vasodilation, so it might be good to play with some light weights after injection with care for balance issues caused by low blood pressure.
I'm rather hard set against the bisphosphonates but (with grace for you pcp) intelligent opinions differ. I like to say that if you see three specialists, two will label you noncompliant.
Like Mablin, I suspect a dxa at three months may not be reflective of benefit. Bone markers might be more revelatory as at three months as P1NP
You're on my favorite drug.

What do you mean when you say you're "rather hard set against the bisphosphonates"? Won't a person have to take one of them after they finish their course of Forteo? Have you taken any other bone building drugs and, if so, what was your experience with them? Thanks.

ripley,
it is ususal (and may be wise) to take bisphosphonates after Forteo.
When talking about "sealing the gains" we refer to an osteoclast proof coating on the surface of the bone. It prevents the natural process of remodeling that removes the parts of the bones with cracks and fissures and attracts osteoblasts that restore integrity to the bone.
Twenty five years ago there was nothing else. And we were grateful for the fractures it prevented. And not so grateful for the atypical fractures and osteonecrosis of the jaw suffered by some. Bisphosphonates certainly prevented more fractures than they've caused.
Then came (the pth 1-34 miracle) Forteo. The use was limited to two years and the research was devoted to What After. Now though, with the black box gone, now we can take Forteo in repeat doses, with responses as "robust" as the initial application.
My experience is very limited. I've been on Forteo for only a year and won't even know if it is working for me until August, though my nails and bone markers are indicating that it is. I haven't taken other drugs, (even refused chemotherapy) All of should which make my ideas suspect.
If I ever yield to a bisphosphonate it will be risidronate, because it seals the bones and prevents repair for the fewest number of years.
There are adverse events with bisphosphonates less than common, but devastating that I've seen too close.