Vitamin D Not Responding to Supplementation- Seeking Insights
I’m a healthy 46-year-old dealing with persistent insufficient vitamin D levels despite increasing supplementation over the past year, and I’m hoping to hear from others with similar experiences. For several months now, I’ve been taking 40,000 IU of Vitamin D3 per week, but my levels are still not going up.
Additional concerns:
• I have osteoporosis, so getting my vitamin D levels up is crucial before starting treatment.
• My PTH (parathyroid hormone) has been mildly elevated at times, but my specialist does not believe it’s a major factor.
• My cholesterol has significantly increased despite no dietary changes, and I wonder if there’s a connection.
• I maintain a balanced diet, including dairy and other calcium sources, and exercise regularly, including weight-bearing activities.
Has anyone here experienced vitamin D resistance or poor absorption?
Did you find any underlying cause (gut issues, genetic factors, or something else)?
What strategies have worked for you?
Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.
chaiyosef,
chrones or celiac can prevent the absorption of D. Are you taking D2 or D3? There is an intramusular injection that would avoid malabsorption issues in the small intestine.
Your kidneys convert D to useable D. Low kidney function can cause hyperparathyroidism.
But fluctuating levels of PTH can be indicative of primary hyperparathyroidism. I'd want my parathyroids checked before any starting treatment for osteoporosis.
Thanks for your input! I’ve been working with specialists, and my nephrologist does not suspect kidney issues. My parathyroid function has been evaluated, and while my PTH has fluctuated, my specialist does not think it’s a primary issue. I’m taking D3, and I’ve been increasing my dose significantly over the past year, but my levels still aren’t rising. Celiac hasn’t been ruled out completely, but my nephrologist doesn’t think it’s likely. That’s why I’m wondering if there are other absorption-related factors I should be considering.
Hi
It's better absorbed if you do the liquid drops d with k. Are you doing pills?
Hi and thanks for your input. I’ve been taking liquid drops without K, but I recently started splitting up the dose and taking it with olive oil to see if that helps absorption. After my next blood results, if I see no change, I plan to switch to 50,000 IU weekly, which was recommended by a specialist. Have you personally noticed a difference when adding K?
Hi @chaiyosef
I always had an issue increasing my vitamin D. Was as low as the 20’s and at best in the mid 30’s. And I’ve taken 5,000 IU daily for years.
A few months back someone in another support group mentioned that if you do not get enough magnesium, the vitamin d does not get absorbed.
So I started taking 400 mg of magnesium citrate, and my last blood test showed a vitamin d of 52 ng/ml
Adding the magnesium was the only thing I changed.
Do some research on this and see if you think it’s right for you.
Good luck.
Thanks for sharing your experience! That’s really interesting. I haven’t focused much on magnesium, but now I’m curious. My vitamin D has been stuck despite high doses, so maybe this is worth looking into. Did you happen to check your magnesium levels before supplementing, or did you just start taking it?
Hi
My endocrinologist told me to always take vit d with k it helps it absorb. You can buy it together
No I did not check my magnesium level, but from what I understand blood serum levels of magnesium are not accurate.
I use Cronometer to track my micro and macronutrients. The 400 mg of magnesium citrate is actually 64 mg of elemental magnesium, I’ve never gone close to over the recommended amount in a day.
Hope his helps.
I have been taking vitamin D3 with K2 , which helps with absorption which was recommended by a natural path doctor. This has helped me maintain a normal level which I have been struggling with ever since having breast cancer.
Thank you for sharing your experience. It sounds like you’ve been through a lot, and I appreciate you taking the time to offer insight. Wishing you continued strength and good health.