Treatment for Prostate Cancer Metastasized to Bones

Posted by cal77 @cal77, Aug 27, 2023

4 months ago diagnosed with Prostate Cancer that has Metasized into Bones. So far, just getting Hormone Treatment...Eligard and Erleada....Feeling so tired...Is this normal? Is there any other treatment available?

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I had 3 infusions of Pluvicto and had to stop it. No side effects except that my PSA started out at 1.56 and ended up at 20.83 after the 3rd. I'm interested to see if anyone else had this problem. I'm now on Jevtana and Carboplatin at the same time. My PSA is fluctuating around 20 now. It has started to rise by 1 to 2 points every 3 weeks. Much slower but concerning. This is the second go around for Jevtana. They added Carboplatin along with it. No side effects but a little fatigue. Biggest problem besides the PSA is the Nuelasta shot to bring up the WBC. It's giving me body aches for up to 7 days. I'm trying various combinations to combat that, any advice would help. I feel pretty much normal for 2 weeks every month. Anyone that wants to know my journey just ask. I'm going on my 10th year of the battle. I'm 62 years old now and I will never give up.

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Yes
Shoulder, lymph nodes and retroperoneal
65
No
Yes

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Profile picture for round5 @round5

Mine is in totally different areas than yours and our age and our journeys are totally different so don’t think our prognosis would be comparable. 2-5 years is what I was given by the chemotherapy doctor but has not been discussed with the Pluvicto team. What I can tell you about Pluvicto as they told me the success rate is as follows:
33% do very well
33% mediocre
33%fail

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Are you Stage 4? Where is cancer? How old are you pls? Were you on Xtandi /Enzalutamide?

Did you get a chance to see success rates here
https://airomedical.com/blogs/articles/lutetium-177-psma-therapy-everything-you-need-to-know#what-is-the-success-rate-of-lutetium-177

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Profile picture for melcanada @melcanada

They have not done my PSMA scan for eligibility yet and clinical trial closing soon They say branch of trial is random If chemo I would stay local hospital and not do trial. I see you can travel 3 days after and if flying must notify TFSA
Did they talk survival with you and what was said?
This if interesting I am Stage 4 in bones L2 T10 11 moving up T 76 7 but very small load But 2,3 x 2,3 in upper chest bone L1 was radiated out in 2020
Where is yours ?
Of great interest
https://airomedical.com/blogs/articles/lutetium-177-psma-therapy-everything-you-need-to-know#what-is-the-success-rate-of-lutetium-177

Jump to this post

Mine is in totally different areas than yours and our age and our journeys are totally different so don’t think our prognosis would be comparable. 2-5 years is what I was given by the chemotherapy doctor but has not been discussed with the Pluvicto team. What I can tell you about Pluvicto as they told me the success rate is as follows:
33% do very well
33% mediocre
33%fail

REPLY
Profile picture for round5 @round5

They do blood work before treatment and a special scan the day after treatment. In-between treatments at the 3 week mark they want blood work done but you can have that done locally and fax it to them. I’ve had some increased fatigue with it a little nausea for a week or so after.

Jump to this post

They have not done my PSMA scan for eligibility yet and clinical trial closing soon They say branch of trial is random If chemo I would stay local hospital and not do trial. I see you can travel 3 days after and if flying must notify TFSA
Did they talk survival with you and what was said?
This if interesting I am Stage 4 in bones L2 T10 11 moving up T 76 7 but very small load But 2,3 x 2,3 in upper chest bone L1 was radiated out in 2020
Where is yours ?
Of great interest
https://airomedical.com/blogs/articles/lutetium-177-psma-therapy-everything-you-need-to-know#what-is-the-success-rate-of-lutetium-177

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Profile picture for melcanada @melcanada

Do they do CT scans and nuclear scans after every injection Bloodwork how often

Any side effects so far

Jump to this post

They do blood work before treatment and a special scan the day after treatment. In-between treatments at the 3 week mark they want blood work done but you can have that done locally and fax it to them. I’ve had some increased fatigue with it a little nausea for a week or so after.

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Profile picture for round5 @round5

Too early for me to comment on one versus the other. Receiving Pluvicto is easier,, less medications involved and it’s only every six weeks versus chemo every three weeks.

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Do they do CT scans and nuclear scans after every injection Bloodwork how often

Any side effects so far

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Profile picture for melcanada @melcanada

are there lots of test scans and blood work meeting in between i would have a 2 hour journey both ways

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Too early for me to comment on one versus the other. Receiving Pluvicto is easier,, less medications involved and it’s only every six weeks versus chemo every three weeks.

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Profile picture for round5 @round5

I’ve had no significant side effects from either. Nausea and fatigue but nothing extreme. Too early to comment on effectiveness since I’m still in the middle of it.

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are there lots of test scans and blood work meeting in between i would have a 2 hour journey both ways

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Profile picture for round5 @round5

I’ve had no significant side effects from either. Nausea and fatigue but nothing extreme. Too early to comment on effectiveness since I’m still in the middle of it.

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Good going Would you have chosen chemo over 177 knowing anything different now

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