Travel & timing after local recurrence

Posted by bblz @bblz, 6 hours ago

Hello. I have appreciated people's openness and support on this site. This is my first time posting.

My 64-year-old husband was diagnosed with PDAC in March 2025, had Whipple surgery that month (clear margins, moderately differentiated, small tumor, but 5 lymph nodes positive for cancer). Starting in April 2025, he had 6 months of often-brutal folfirinox treatment (with doses of some agents modified as treatment progressed, and the oxaliplatin discontinued after 5 rounds due to bad neuropathy), with chemo ending Sept 2025.
He has been working hard to rebuild his strength, has regained weight, is doing 90 minutes of intense biking indoors--soon to try outdoors, and overall, except for neuropathy in his feet which makes it hard to walk long distances, is feeling well.

A few weeks ago, routine monitoring found an elevated CA 19-9 and he subsequently had CT scans (earlier than had been planned). While the chest CT was clear, the abdominal CT found evidence of a local recurrence in the surgical area. He has no symptoms.

He is scheduled to have SBRT (strong, targeted radiation to the area of recurrence) for 5 days, starting in a few weeks (the earliest that the fancy machine at Dana Farber here in Boston is available). He then will have scans and CA 19-9 testing every 2 months.

We've been told to expect further recurrence and then progression from there, which could happen soon or could be a little while. (Wish we had a crystal ball.) At that point he would most likely need to go on gemcitamine/abraxane, or maybe some kind of trial.

His favorite thing to do is to travel places off the beaten track, preferably with loved ones. We would like to go on one more "big trip" with our young adult kids and their partners. The best time for the 7 of us to get away together is late December.

We are considering going to Tanzania for a safari. (We're also looking at going on a Galapagos trip... my husband would like to go to Southeast Asia…Morocco...we're fairly well-travelled...open to ideas).

We would purchase extensive travel insurance, and go where we would be able to get to a hospital in a city within a few hours, and would get insurance that would allow him to be medically evacuated if necessary.

Is this a crazy idea? There's a reasonable chance that by then he will be on systemic chemo. Has anyone done any big travel along these lines while on chemo? Anyone have experience with living disease-free/progression free following treatment for local recurrence? Should we book the trip?

Advice, experiences, ideas are welcome. Thank you.

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