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Transitioning from Plaquenil (hydroxychloroquine) to Methotrexate

Posted by nettsie @nettsie, 2 days ago

Transitioning from Plaquenil (hydroxychloroquine) to Methotrexate
Posted by nettsie @nettsie, 2 days ago
My doctor has recommended switching from hydroxychloroquine to Methotrexate. As explained I would continue taking hydroxychloroquine for about a month while starting with a low dose of Methotrexate.
I would appreciate hearing about anyone's experience with this.
Thank you.

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maymore | @maymore | 1 day ago

Methotrexate (MTX) can negatively affect bones, leading to osteoporosis, bone pain, and fractures, especially at the high doses used for cancer, but even lower doses for arthritis can sometimes cause issues (called MTX osteopathy). I took methotrexate for my rheumatoid arthritis when I was young and now I have severe osteoporosis.

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grrranny | @grrranny | 1 day ago
In reply to @maymore "Methotrexate (MTX) can negatively affect bones, leading to osteoporosis, bone pain, and fractures, especially at the..." + (show)
Profile picture for maymore @maymore

Methotrexate (MTX) can negatively affect bones, leading to osteoporosis, bone pain, and fractures, especially at the high doses used for cancer, but even lower doses for arthritis can sometimes cause issues (called MTX osteopathy). I took methotrexate for my rheumatoid arthritis when I was young and now I have severe osteoporosis.

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@maymore Same with my 84 year-old husband, who has severe kyphosis and now has his 6th spinal compression fracture. Doctor has only blamed it on Rheumatoid Arthritis.

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profcnrn | @profcnrn | 8 hours ago

Hydroxy to Methotrexate… You didn’t mention your Diagnosis?

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