I’ve tried tramadol a number of times without success for headache, back and neuropathic pain, but always at low and apparently less than effective doses such as 50 mg twice a day. I tried it today at a single 100 mg dose and got significant headache relief and even a little kicker in mood. My neurologist encouraged me to try it PRN and he may be onto something. I’m pretty placebo resistant so I wonder if anyone else has had success with pain issues, and possibly mood as well, with doses up to 300 – 400 mg of tramadol.
Also interested in side effects since its not supposed to depress respiration, at least as badly as opiates. It may however interfere with sleep, specifically stage 3 slow wave.
Any thoughts or insights appreciated.