The treatment begins. I hope it makes sense.

Posted by stew80 @stew80, 21 hours ago

After 'clean' scans and a biopsy showing Gleason 9 with cribriform and PNI, the Urologist's office (nurse practitioner) called to say they want to start me right away on Casodex for 30 days, and prescribed an Eligard injection (to be given in 10 days). That coupled with an appointment in June with a radiation/Oncologist. That's all I know until I have my formal meeting with my Urologist to review all the results and I guess a recommended treatment plan. Does this sound like a typical beginning?

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I have similar set up. G9, PNI, no spread. Working with center of excellence in S Florida. I’m 61 in excellent shape. I’m leaning towards starting ADT( Orgovyx and apalutamude) for several months and then having RP. Surgeon thinks he can get good margins. This is not a typical protocol but I’m going to try it. It’s aggressive cancer.. I want to be aggressive. I’m also getting 2nd opinion from Mayo Jax. Good luck.

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This sounds like a good treatment plan. You might prefer taking Orgovyx. It’s a pill you take once a day. It replaces the Casodex and the Elgard injection. When you stop taking Orgovyx Your testosterone comes back much quicker than with Eligard. You will probably be on these drugs for 24 months.

Almost all insurance plans cover it now. It works just as well as the Eligard shot. Ask your doctor for it.

Cribriform is very aggressive, Another reason this treatment plan makes sense.

With the Gleeson nine, the ADT treatment will Usually stop your cancer from Growing and can shrink it for radiation.

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TM I am G9 CR advanced incurable etc.with a poor prognosis I had lupron and erleada 6 months then RP then these same drugs for another 6 months. That started 40 months ago and I have remained undetectable. Now 78 and I am exceeding my doctors and my expectations Your doctors recommendations sound similar to my doctor Good luck to you and all

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Stew, it sounds very proactive, which is good…Orgovyx might be a better choice for ADT.
And most importantly, I think you mentioned you are 83. I firmly believe that surgery is NOT an option for an 83 yr old man. I may risk the wrath of Colleen for saying that but you are too freakin old to go thru that and then STILL need radiation in a few months or a year.
There are plenty of radiation based options which have varying side effects, but nothing as bad as surgery at your age.
There’s HDR brachytherapy with SBRT….SBRT alone….IMRT, etc.
If you were anywhere up to maybe 70 yrs of age, surgery would be an option due to the fact that a longer anticipated lifespan might allow for recurrence; at 83, not so much….Best
Phil

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Thanks Phil. I agree with you regarding surgery. Radiation and ADT seems like the way to go. They hinted about brachytherapy (I'll know more in June) but I heard the doesn't work well if a previous Turp has been done. I had a Turp several years ago.
I'll ask about Orgovyx (Relugolix). I don't hear much about it here for some reason although I know it was approved for use several years ago in Canada.

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