What's your experience with Orgovyx (relugolix)?

Yes, I think the insomnia was the most annoying thing, since I am usually a sound sleeper. All good now 3 months post Orgovyx.

I'm 1-1/2 months in Orgovyx. I woke up 4 times after midnight feeling a little bit hot in the body and cold legs as if they were a little wet for a couple minutes, and then I would be okey as if nothing happened. My worst experience to date.
I finished my SBRT treatment 18 days ago; my oncologist said that my immediate side effects would probably peak around the third or fourth week. I will see what happens next week. After that I hope things will get better.

It’s actually not that new. It uses estradiol to suppress T. Less side effects due to the fact that it is absorbed thru the skin and does not go thru the liver (doesn’t raise enzymes).
Phil

My cancer came back after a RP 2 years to the date after removal. No spread per PSMA Pet at that time. Keep in mind that test is good for that day and it also needs a tumor around 2.7 mm in size to see, so I have heard. My PSA had risen to .22, BCR. There is a mysterious margin slide that my surgeon denies but noted by both RO and second opinion Genitourinary Cancer specialist last week that is the suspect. Surgeon will be relegated to blood tester. Any future treatment will be done at our local Comprehensive Cancer Center.
Cells can work their way out of the prostate into the bed or left behind if your surgeon cuts the margins to close trying to save nerves.
They get paid, we get adt and zapped. I've heard the same story many times on this thread. The Genitourinary specialist at the CCC cancer that I had a second opinion with last week told me to hold off on any future treatments and wait 6 months after ADT to get my next PSA test. Also told me to come see him if my PSA rises to 2 (not 0.2) and he will find it and treat it. After 3 mos. on ADT and 6 weeks after radiation my PSA is 0.014 which is as low as it can be measured at my facility. Stated my greatest risk is being overtreated.

Has anyone tried the new “Patch” that is out there , that is supposed to be the NEW hormone therapy ? If so how did it work. My Urologist never heard of it.

To add to my earlier response, yes, I had prostatectomy and then RT. And due to rising PSA, that is when I agreed with my Hematologist to take Orgovyx hormone therapy.

There must have been some cancer cells left after prostatectomy, and then was not totally irradiated after going for RT, so they started to spread out. But I am happy now that my PSA is down to .1 after 6 months on Orgovyx. It’s true I have hot flushes but to me, it’s just like a little sweat out. But what I observed is that my testicles disappeared, and no libido. I read from some bloggers here that one taking Orgovyx tried taking Cialis 5mg at the same time while taking Orgovyx and he had erections after a few months. I just tried last week and it’s true. I am like back to my younger days again. My partner is surprised, he he.

What a coincidence that @myash and I take Orgovyx approximately the same hour.
I am a good sleeper; the hour I take meds doesn't affect my sleeping pattern.

I’m a bad sleeper anyway so I’m not sure if it’s affecting me. I take sleep meds also.

Thanks. Do you think taking it at that time is affecting your sleep? That’s what would concern me.