Connect
Anyone have stomach pain while on Enzalutamide (Xtandi)?
My father has stage 4 prostate cancer and on Enzalutamide for past 2 years. He is currently having unbearable pain in his stomach and around the ribs. Does anyone had that issue while on Enzalutamide madication or in general as a side effect of this disease.
Like
Helpful
HugInterested in more discussions like this? Go to the Prostate Cancer Support Group.
Connect
This is not a normal issue with Enzalutamide. Even though he is on Enzalutamide And his PSA may show it’s undetectable, Metastasis can occur and cause issues.
If his PSA is undetectable, then a PSMA pet scan may not show anything, But in cases of large Metastasis it does show up.
In this case, a CT scan may be useful to compare previous to current.
Darolutamide Works very much like Enzalutamide, But has fewer side effects. If they can’t find something wrong with scans, then maybe changing the drug will make a difference.
-
Like -
Helpful -
Hug
3 ReactionsI'm on Apalutamide and get regular digestive pain like the OP's father's situation, but not as severe (just uncomfortable, not unbearable). While it might be from the Apalutamide in my case, I think it's more likely from my spinal compression, which can lead to nerve hypersensitivity. It could also (less likely) be a side-effect of surgery or radiation.