Statin Induced muscle pain and stiffness

Posted by kathleenverna @kathleenverna, 2 days ago

My Crestor was increased and I was also taking an antifungal fluconazole. A month later, I developed severe muscle pain, stiffness in buttuck and thigh and foot tingling. Stopped statins and PCP advised taking Coq10. If anyone has gone through this, how long to resolve??

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To be honest I am going through this same issue. How long have you stopped the statins and do you still have symptoms. I'd be interested to see if just the CoQ10 alone reduces it. My cholesterol was like 270 or so and I have issues taking statins. Before my knee replacement I used Praluent (injection) and didn't seem to have any issues. I feel like now that I am back on it I have more muscle pain than without. I'm stopping it for a month again to see what happens. If I can't take oral statins or the injection now maybe so I'm not sure. I already take CoQ10 every day. If you eat right and still have high cholesterol not sure what they can even do. It's frustrating. Not sure if my pain is due to the knee replacement (it's been over 2 years), if it is the Praluent or if it just exacerbates the muscles issues that are already there.

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@kathleenverna
I was put on Atorvastatin almost 10 years ago. I was advised it could cause muscle pain. I was put on the 40 mg. and advised to take Co-Q10 from both my cardiologist and HF doctor. I did not have muscle pain.

My wife was put on a statin but was not told to take Co-Q-10 and she developed muscle pain. I told her about co-Q-10 and to talk to her PCP about taking it for muscle pain. She did and he said take it. She went on Co-Q-10 and it helped reduce her muscle pain. It is not a cure all but worth trying (if your doctor approves) to see if can help.

There is a lot of information out there about co-q-10. One is that it is not easily absorbed. An enhanced type of Co-q-10 called ubiquinol is better absorbed but is much more expensive. What do I take, both.

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Check for drug interactions when taking a statin.
Various sites online have easy to use window apps to fill in and cross check. The fluconazole interacts with statins.
There are positive benefits of CoQ10 as a stand alone supplement. Like the statins it has some anti-inflammatory activity.

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@jc76

@kathleenverna
I was put on Atorvastatin almost 10 years ago. I was advised it could cause muscle pain. I was put on the 40 mg. and advised to take Co-Q10 from both my cardiologist and HF doctor. I did not have muscle pain.

My wife was put on a statin but was not told to take Co-Q-10 and she developed muscle pain. I told her about co-Q-10 and to talk to her PCP about taking it for muscle pain. She did and he said take it. She went on Co-Q-10 and it helped reduce her muscle pain. It is not a cure all but worth trying (if your doctor approves) to see if can help.

There is a lot of information out there about co-q-10. One is that it is not easily absorbed. An enhanced type of Co-q-10 called ubiquinol is better absorbed but is much more expensive. What do I take, both.

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My husband took it for a few months and his liver lab results were not good, in ultrasound you can see a start of a fat liver( no Alkohol)
We have an appointment with his cardiologist and Internist this week, stopped the statin by ourselves.

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@cindymattern

To be honest I am going through this same issue. How long have you stopped the statins and do you still have symptoms. I'd be interested to see if just the CoQ10 alone reduces it. My cholesterol was like 270 or so and I have issues taking statins. Before my knee replacement I used Praluent (injection) and didn't seem to have any issues. I feel like now that I am back on it I have more muscle pain than without. I'm stopping it for a month again to see what happens. If I can't take oral statins or the injection now maybe so I'm not sure. I already take CoQ10 every day. If you eat right and still have high cholesterol not sure what they can even do. It's frustrating. Not sure if my pain is due to the knee replacement (it's been over 2 years), if it is the Praluent or if it just exacerbates the muscles issues that are already there.

Jump to this post

I stopped the Crestor and fluconazole just 2 1/2 weeks ago. Started 200mg Coq10 at that time. Muscle weakness is gone, pain better during the day, but still intense upon awakening. Very slow going.

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@kathleenverna

I stopped the Crestor and fluconazole just 2 1/2 weeks ago. Started 200mg Coq10 at that time. Muscle weakness is gone, pain better during the day, but still intense upon awakening. Very slow going.

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I am due this Thursday for another shot and think I may leave it off. It's every other week and the bad thing about the shots is that it takes longer to leave your system unlike the pills. I take 100mg Coq10 and may increase to 200 for a time. Definitely worse upon waking and going to bed. I just want my stamina in me legs back. It's like a double whammy with my knee thrown in as they had to cut muscles I believe. I already have arthritis several places and statin can't be helping but how do we get it down if we can't take them. I take the Qunol Coq10, Centrum Silver and Mega red (fish oil)

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I also have arthritis - facet joint osteoarthritis - which made the connection to statins very elusive and difficult! Wishing you the best and mat God bless you in your healing process.

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@cindymattern

To be honest I am going through this same issue. How long have you stopped the statins and do you still have symptoms. I'd be interested to see if just the CoQ10 alone reduces it. My cholesterol was like 270 or so and I have issues taking statins. Before my knee replacement I used Praluent (injection) and didn't seem to have any issues. I feel like now that I am back on it I have more muscle pain than without. I'm stopping it for a month again to see what happens. If I can't take oral statins or the injection now maybe so I'm not sure. I already take CoQ10 every day. If you eat right and still have high cholesterol not sure what they can even do. It's frustrating. Not sure if my pain is due to the knee replacement (it's been over 2 years), if it is the Praluent or if it just exacerbates the muscles issues that are already there.

Jump to this post

We stopped it a week ago when we saw the lab results.
His cardiologist mentioned anyway to stop the statin and put him on Repatha again.
We changed the prescription plan for 2025 and Repatha is on it now.

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@cindymattern

To be honest I am going through this same issue. How long have you stopped the statins and do you still have symptoms. I'd be interested to see if just the CoQ10 alone reduces it. My cholesterol was like 270 or so and I have issues taking statins. Before my knee replacement I used Praluent (injection) and didn't seem to have any issues. I feel like now that I am back on it I have more muscle pain than without. I'm stopping it for a month again to see what happens. If I can't take oral statins or the injection now maybe so I'm not sure. I already take CoQ10 every day. If you eat right and still have high cholesterol not sure what they can even do. It's frustrating. Not sure if my pain is due to the knee replacement (it's been over 2 years), if it is the Praluent or if it just exacerbates the muscles issues that are already there.

Jump to this post

I don't like the side effect of digestive problems at 76 y.o.

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You guys are all over the place with the conversation. The first person sounds like they have sciatica. The last person has digestive problems and the ones in the middle have arthritis. none of this stuff is related or causal to the statins! My dad took statins for 25 years NO PROBLEMS. Lowered his cholesterol from 369 to 196 or 169. I took them for 3 weeks and got the muscle weakness/pain issue and dr. took me off. Please, please, talk to your doctors. Also, please read the scientific literature and not the antidotal stories. Most of Coq10 is a myth except when it comes to Heart Failure. https://www.ncbi.nlm.nih.gov/books/NBK531491/

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