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Starting Chemo Taxotere/docetaxel, what to expect?

Posted by bruceconstantine @bruceconstantine, 4 days ago

I have been diagnosed with Gleason 4 + 4 = 8, group 4 PC. Currently on Lupron and Nubeqa. Will be adding Taxotere to my regiment shortly. What should I expect for side effects?

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jeff Marchi | @jeffmarc | 4 days ago

Due to their different mechanisms of action. ADT which includes Orgovyx, Firmagon, Lupron, Eligard, Prostap, Camcevi, Lucrin, Zoladex, Trelstar, Pamorelin, and Decapeptyl can cause numerous side effects. These are actually due to a lack of testosterone.

Hot flashes
Fatigue
Muscle deterioration
Bone weakening
Brain fog
Depression
Weight gain
Difficulty in breathing

Not everyone gets all of them.

They should’ve told you to get on calcium and vitamin D. Need to exercise a lot, that will Really help reduce fatigue. Not sure how much you’ve looked into this, but there are many videos on exercise and prostate cancer because of the fatigue, bone and muscle Deterioration, if you do not exercise and do some weight training.

Another thing is, you need bone strengthening because these drugs really chew up your bones. Fosamax, Zometa, Or Xgeva are common drugs used to do this. If your doctor has not brought this up, you should mention it, In a webinar, I went to, a Doctor Who specialize in bones, said that everybody on ADT should be on bone straighteners.

Chemo does not change your life, Yes, while you are on it, it can be not too bad or a real pain, Again, no two people are the same. I was in an Ancan.org Advanced prostate cancer meeting and one guy came in and said he was doing chemo but after doing chemo, for 10 days, he couldn’t eat food, didn’t taste good. He lost a lot of weight then he’d have a few days where he’d recovered completely, ate a lot of food, then back to the next chemo session. The other people that said they were just uncomfortable for a few days after, had to rest to recover.

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1 reply
bruceconstantine | @bruceconstantine | 4 days ago
In reply to @jeffmarc "Due to their different mechanisms of action. ADT which includes Orgovyx, Firmagon, Lupron, Eligard, Prostap, Camcevi,..." + (show)
@jeffmarc

Due to their different mechanisms of action. ADT which includes Orgovyx, Firmagon, Lupron, Eligard, Prostap, Camcevi, Lucrin, Zoladex, Trelstar, Pamorelin, and Decapeptyl can cause numerous side effects. These are actually due to a lack of testosterone.

Hot flashes
Fatigue
Muscle deterioration
Bone weakening
Brain fog
Depression
Weight gain
Difficulty in breathing

Not everyone gets all of them.

They should’ve told you to get on calcium and vitamin D. Need to exercise a lot, that will Really help reduce fatigue. Not sure how much you’ve looked into this, but there are many videos on exercise and prostate cancer because of the fatigue, bone and muscle Deterioration, if you do not exercise and do some weight training.

Another thing is, you need bone strengthening because these drugs really chew up your bones. Fosamax, Zometa, Or Xgeva are common drugs used to do this. If your doctor has not brought this up, you should mention it, In a webinar, I went to, a Doctor Who specialize in bones, said that everybody on ADT should be on bone straighteners.

Chemo does not change your life, Yes, while you are on it, it can be not too bad or a real pain, Again, no two people are the same. I was in an Ancan.org Advanced prostate cancer meeting and one guy came in and said he was doing chemo but after doing chemo, for 10 days, he couldn’t eat food, didn’t taste good. He lost a lot of weight then he’d have a few days where he’d recovered completely, ate a lot of food, then back to the next chemo session. The other people that said they were just uncomfortable for a few days after, had to rest to recover.

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Thanks for the info, very informative.
I am taking a calcium and vitamin d supplement also. I'm in a cardiac rehab program 3 days a week at the gym with cardio and a little weight lifting. The exercise definitely helps with the fatigue. Also scheduled for a bone scan in August and then we'll evaluate for bone density meds.
Thanks again for the info

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