Received the news on Halloween. I have prostate cancer. Need advice.
I previously had 2 benign biopsies in 2024. Urologist/Oncologist asked to follow up in a year. So on September 2025, I did PSA (5.4) and MRI (2 legions PI-RADS3, and PI-RADS4). These 2 legions are similar in size with the previous 2 MRI's from 2024.
Doctor ordered a biopsy. On Halloween day, the report came and it shows out of 18 cores, there are 2 Gleason 6, and 1 Gleason 7 (3+4), which is with 40% core, and G4 is 10%.
I am scheduled to see my Urologist/Oncologist on Wednesday. I will ask for a Decipher or Polaris test and a PSMA scan. Maybe a genetic test to check BRCA1, BRCA2 genes?
I am not sure what else to ask from the doctor. Any advice will be greatly appreciated.
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@kenhorse I think you have a lot more knowledge on this front than I do, so I am glad you weighed in, Ken.
If anything, they came up with a hypothesis and then worked backwards to ‘prove’ their theory. That’s not a scientific study and unfortunately, neither is the questionnaire model where you ask people to be honest about their own habits…good luck with that!!
Phil
There is a HUGE difference in the frequencies used by landline cordless and cell phones as well as the amount of transmitted power each can generate.. And that means a HUGE difference in effect (which is mostly tissue heating anyway as they are BOTH non-ionizing radiation (nothing in common with gamma rays, x-rays or any of those).
That "study" is garbage
@lyricw OK…I read the complete study twice and nowhere does it talk about the phone being in the front hip pocket - even though the photo at the top of the article is a man’s denim clad hips with a cellphone poking out of it… totally misleading, isn’t it?
Also, they compared PCa cases using cordless phones as well, not just mobile. They claim the highest grade cancers occur in men who used either type of phone…really? How many men today use a landline phone? I have one and seldom use it.
Officeworkers, unless they are using headsets, almost always use their cellphones, even with a landline sitting right in front of them.
Also, they tried to equate the highest Gleason scores to phone use…and failed because their rationale is akin to saying, ‘ A large cohort of Men who breathed air in their homes, had high Gleason scores…’
That said, nothing would surprise me concerning brain cancer incidence in the older satellite type phones - the power was continuous and the antenna was your head!!
BTW, I had never used a cell phone in my life and rarely used a cordless one up until the day of my diagnosis of Gleason 4+3 unfavorable at age 64; It is only over the last 4 yrs that I use one….so??
I am not a fan of high frequency radio waves zipping all around us, PFOA’s (which the article also mentions) and other environmental factors as yet unknown, but there is no solution to these modern problems other than living off the grid like a hermit…not gonna do that with what little time I have left! Great find, BTW…
Phil
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2 Reactions@cward0624 , @frank1956
Options should be stay on AS as long as one can, then Tulsa Pro (maybe hifu in a few cases, and maybe a new one called vanquish), then as last resorts are RP or radiation. Tulsa Pro is in a new form since mid- 2023 not many places have it. You may have to travel somewhere, that is not that big a deal, use AirBnB places to stay during procedure if needed.
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Tulsa
https://tulsaprocedure.com/find-a-tulsa-pro-center/
https://tulsaprocedure.com/
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1 Reaction@jeffmarc Gleason 7 (
4+3 75%).
On my MRI they said two tumors PiRADS 5. Mayo reviewed it and said PiRADS 3. Originally on the biopsy it was a proposed Gleason 8 (one core was 4+4 with intraductal. ) Post surgery no intraductal found. Cribriform pattern was in the final pathology report but no immediate concern since pathology and PSMA/CT were clean. Gleason set at 7.
I did have a minor ECE (Extracapsular Extension) so we will monitor appropriately. Do I have a higher chance of recurrence? Possibly. But the treatment options keep growing. At my age 10 years is a lifetime.
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1 ReactionHello Frank. It looks like you’re covering all bases. I’m 77 and been on AS for over twenty years at Hopkins. Until 2025 about 15 biopsies came back negative or 3+3. (Most were 3+3). In June 2025 a biopsy came back 3+4 with 5% or less 4 and no large cribriform in one of the cores. Hopkins recommended radiation. I went to another center of excellence for a second opinion on continuing AS and that center obtained and read the slides from the Hopkins biopsy as 3+3!! My Decipher was .50. So things are murky. Although my PSA is around 20 I’m sticking with AS for now.
Anyone seen this: carrying cellphone in front pocket linked to prostate cancer?
https://www.ehn.org/prostate-cancer-cell-phone-use
@chuckb
What was your final Gleason score?
I had similar findings this August but slightly worse. I got a 2nd opinion at Mayo Rochester and they downgraded it and downgraded again after my biopsy. I had my prostatectomy on Halloween (they didn't wear costumes) and both it and the biopsy were virtually pain free. A benefit of surgery is that the can do a pathology report. In mine it showed everything to be clean with clear margins-and they downgraded again. There are a couple of side effects that everyone is concerned about but the vast majority of men recover from them. But, there are similar and sometimes worse side effects with radiation that show up much later. You might want to look them up. I'm 75, in otherwise good shape and am confident something else will get me, even if it returns in 10-15 years when new treatments can be applied. Best of luck. Remember that each specialist will recommend their treatment.
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3 Reactions@frank1956
Seems to me Frank you are doing everything you can to help you make decisions on what is best for you. Getting opinions and second opinions is something many of us do to help make decisions on what treatment you decide.
I did not have RP so can only mentioned what others have posted and will leave comments on RP to others that have had it as cannot add any personal experience to you.
You had the Decipher which I would have recommended as was really a deciding factor in what I chose and my doctors chose for my treatments.
You are doing a lot of research on your own and reading directly that research so in my opinion you are right on tract on what to do to help with decisions.
Good luck!!
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