Radiation or not after surgery for endometrial cancer?

Posted by marceyw @marceyw, Feb 4, 2024

I was diagnosed with early stage endometrial cancer at Christmas. Had complete hysterectomy on 1/9/24. There was no cancer in the sentinel lymph nodes, ovaries or tubes. My doctor is suggesting brachytherapy to cut my 10% chance of recurrence to 5%. I’m concerned about the side effects. Has anyone been thru this and what are the possible side affects of this type of radiation? Dr said I don’t have the harmful P53 gene but do have a gene that would qualify me for immunotherapy if it were to come back. Really torn about what to do next. Would like to think I could fight the return with diet and lifestyle. Ideas and experiences appreciated.

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Hi- Revaree plus is a suppository as well- you have to insert with finger- no applicator- and the next day you should wear a mini pad since it does stain a bit. The name of the online site is called bonafide to order from- they have specials on subscriptions. They also offer other products. I have been using for years since the brachytherapy dried me out. I am 77. There is revaree and revaree plus- I am now using plus.

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I had stage 1B Grade 3 endometrial cancer treated with complete hysterectomy 3 years ago. Surgery was followed by 3 brachytherapy radiation treatments. The vaginal brachytherapy was not difficult at all (and I was 82 then). I’ve had no recurrence of cancer thus far.

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Profile picture for bocabird @bocabird

@naturegirl5 I use revaree plus-but I don't have sex anymore- this i hyaluronic acid- keeps the area moist and non itchy- I had brachytherapy- diagnosed with stage 1a-2 serous papillary endometrial- two separate opinions said brachytherapy would protect the vaginal cuff from recurrence-so far so good- diagnosed in May 2017/ Also had 6 rounds carboplatin and taxol

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@bocabird I know about Revaree Plus. Do you purchase this over-the-counter? I have been using Hyalo-Gyn for 4 years. It keeps the vagina moist and the formula does not itch or burn. It can only be ordered online and their online site is wonky and does not always work. I get Hyalo-Gyn by a subscription in the suppository form as I find the creams to be messy. I'm going to compare Revaree Plus to Hyalo-Gyn for the sake of convenience.

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I had both external beam pelvic radiation and brachytherapy. With the brachy, we are committed to using a dilator for the rest of our days to avoid atrophy and to enable internal exams. Pelvic radiation has many long term side effects that can pop up years afterwards, which I find more life-interruptive than dilator use.

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I'm still recovering from hystrectomy and will probably have Brachytherapy 3 treatments in January. Just to give me peace of mind that if I have a re-occurence in the future I won't have regrets not having the treatments which might have prevented it.

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Profile picture for bocabird @bocabird

@jar1591927 I had serous papillary- which is very serious as well. Stage 1a-2 had two different opinions. Same protocol carboplatin and taxol then Brachytherapy. Diagnosed May 2017- so far so good.

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Stay healthy!

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Profile picture for bocabird @bocabird

@jar1591927 I had serous papillary- which is very serious as well. Stage 1a-2 had two different opinions. Same protocol carboplatin and taxol then Brachytherapy. Diagnosed May 2017- so far so good.

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👍

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Profile picture for jar1591927 @jar1591927

Had brachytherapy 5 treatments to the vaginal cuff following surgery. Recommended because it is a likely place for recurrence.
Have Stage 1a endometrial carcinoma however it is Clear Cell. I had zero problems with the radiation. Nothing.
The radiologist oncologist also has follows me every 3 months. I'm 15 months postop so I have a way to go...clear cell is aggressive and I have the p53 gene. Been told I have done everything I can do at this point. Have the brachytherapy- be cautious but don't skip it if you're worried about side effects. Good luck.

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@jar1591927 I had serous papillary- which is very serious as well. Stage 1a-2 had two different opinions. Same protocol carboplatin and taxol then Brachytherapy. Diagnosed May 2017- so far so good.

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Profile picture for Helen, Volunteer Mentor @naturegirl5

@round2 I did not have cancer before I was diagnosed with endometrial cancer (endometrioid adenocarcinoma, FIGO Grade 1, Stage 1a) in 2019. I had been using estradiol for about 6 years prior to that diagnosis. It's a confusing controversy however my gynecologist and the providers at Mayo's Menopause and Sexual Health Clinic told me that minute amounts of estrogen are absorbed in the bloodstream when administered vaginally - which is essentially as if you are rubbing it on the back of your hand called "transdermal". Still, since my cancer diagnosis my doctors have told me I can no longer use estradiol. I guess it's why take the chance? The estradiol worked very well for me. I now use a vaginal lubricant two times a week that contains hyaluronic acid. You can purchase these products over-the-counter.

Which non-hormonal cream does your doctor recommend?

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@naturegirl5 I use revaree plus-but I don't have sex anymore- this i hyaluronic acid- keeps the area moist and non itchy- I had brachytherapy- diagnosed with stage 1a-2 serous papillary endometrial- two separate opinions said brachytherapy would protect the vaginal cuff from recurrence-so far so good- diagnosed in May 2017/ Also had 6 rounds carboplatin and taxol

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Hi,

I’m in the same situation and need to decide if I go ahead with radiation or not. Diagnosed with endometrial cancer figo grade 1, stage 1A2 after surgery completed on 09.26.2025. Met with radiology dr. and he said its my decision if I choose to do 3 brachytherapy sessions or only the regular follow-up, Did anybody regret doing the brachytherapy? If there is a recurrence in the future, what are the implications of having done brachytherapy already? Thank you

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