Radiation or not after surgery for endometrial cancer?

Posted by marceyw @marceyw, Feb 4, 2024

I was diagnosed with early stage endometrial cancer at Christmas. Had complete hysterectomy on 1/9/24. There was no cancer in the sentinel lymph nodes, ovaries or tubes. My doctor is suggesting brachytherapy to cut my 10% chance of recurrence to 5%. I’m concerned about the side effects. Has anyone been thru this and what are the possible side affects of this type of radiation? Dr said I don’t have the harmful P53 gene but do have a gene that would qualify me for immunotherapy if it were to come back. Really torn about what to do next. Would like to think I could fight the return with diet and lifestyle. Ideas and experiences appreciated.

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So they would still do brachytherapy 2 years after surgery? I'm surprised, they want to do brachytherapy 8 weeks after my surgery, 2 years seems like a long time, but what do I know, I'm not an oncologist

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Given a choice? We always have a choice, no matter what treatment might be offered.........

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I had hysterectomy and all lab tests, no specific tests before brachytherapy. Sentinel lymph nodes clear. If cancer cells escaped, then they can go anywhere as I understand, any organs, liver, lungs, brain, etc... brachytherapy is only in vagina, as I understand, future recurrence needs to be dealt with wherever it might occur.
I don't know if it would preclude external beam radiation, do you know?

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Profile picture for bocabird @bocabird

@jar1591927 I had serous papillary- which is very serious as well. Stage 1a-2 had two different opinions. Same protocol carboplatin and taxol then Brachytherapy. Diagnosed May 2017- so far so good.

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@bocabird It is rare type of endometrial cancer- I too was diagnosed in May 2017! I thought I was reading about myself!! I am in South Florida area- had a second opinion at Moffatt and they upped me from 1a to 2 due to their board seeing some cervical involvement. They did not want the sandwich protocol therapy - I had exactly what you had. Got through it on my own. I believe my osteoporosis is from the chemo. Me too so far so good-the oncologist said I do not need to see him anymore -just my regular gyno. Do you still get checkups with the oncologist?

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Profile picture for 1995victoria @1995victoria

I'm still recovering from hystrectomy and will probably have Brachytherapy 3 treatments in January. Just to give me peace of mind that if I have a re-occurence in the future I won't have regrets not having the treatments which might have prevented it.

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@1995victoria were u given the choice to do brachytherapy or not? What tests will they do before radiation (if any)?
What are the benefits as explained to you? I understand it prevents reoccurrence at vaginal cuff but no benefit if any cancer cells escaped in the lymphatic system.
Should a recurrence happen in the future, what is the impact on having brachytherapy already?
Trying to make a hard decision …

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Profile picture for bocabird @bocabird

@acktiv1 Did you do chemo as well? Also since you must be very dry down there from brachy I suggest revaree plus- sold online by Bonafide company- Congratulations for staying healthy.

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@bocabird I didn’t do chemo. My oncologist and the radiation oncologist recommended five weeks of pelvic radiation but didn’t push me. I didn’t feel strong enough to do that and chose brachytherapy instead. I felt confident that was the right decision for me at my age. I’ve been very fortunate!

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My understanding is that the dilator is for stenosis and atrophy while the creams are for dryness and discomfort, particularly during intercourse.
The Revaree, at least, seems preferable to hormonal creams.
Thanks for sharing.

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Profile picture for Helen, Volunteer Mentor @naturegirl5

@round2 I did not have cancer before I was diagnosed with endometrial cancer (endometrioid adenocarcinoma, FIGO Grade 1, Stage 1a) in 2019. I had been using estradiol for about 6 years prior to that diagnosis. It's a confusing controversy however my gynecologist and the providers at Mayo's Menopause and Sexual Health Clinic told me that minute amounts of estrogen are absorbed in the bloodstream when administered vaginally - which is essentially as if you are rubbing it on the back of your hand called "transdermal". Still, since my cancer diagnosis my doctors have told me I can no longer use estradiol. I guess it's why take the chance? The estradiol worked very well for me. I now use a vaginal lubricant two times a week that contains hyaluronic acid. You can purchase these products over-the-counter.

Which non-hormonal cream does your doctor recommend?

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@naturegirl5 My oncolgist and gyno a few years ago advised using invexxy -an estradiol which I did not want to use.

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Profile picture for ffr @ffr

I had both external beam pelvic radiation and brachytherapy. With the brachy, we are committed to using a dilator for the rest of our days to avoid atrophy and to enable internal exams. Pelvic radiation has many long term side effects that can pop up years afterwards, which I find more life-interruptive than dilator use.

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@ffr I stopped the dilator after one year and had physical therapy. I use revaree plus now twice a week. I have no issues with internal exams -very easy for Dr. Had about 4 brachy-

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Profile picture for acktiv1 @acktiv1

I had stage 1B Grade 3 endometrial cancer treated with complete hysterectomy 3 years ago. Surgery was followed by 3 brachytherapy radiation treatments. The vaginal brachytherapy was not difficult at all (and I was 82 then). I’ve had no recurrence of cancer thus far.

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@acktiv1 Did you do chemo as well? Also since you must be very dry down there from brachy I suggest revaree plus- sold online by Bonafide company- Congratulations for staying healthy.

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